Cerebrospinal fluid biomarkers and memory present distinct associations along the continuum from healthy subjects to AD patients

L Rami, J Fortea, B Bosch… - Journal of …, 2011 - content.iospress.com
The objective was to study the association between cerebrospinal fluid (CSF) levels of
amyloid-β (Aβ) 1-42, t-tau, and p-tau and cognitive performance along the Alzheimer's
disease (AD) continuum from healthy subjects to AD patients and, specifically, among
patients in the pre-dementia stage of the disease. A total of 101 subjects were studied: 19
healthy controls (CTR), 17 subjects with subjective memory complaints (SMC), 47 with mild
cognitive impairment (MCI), and 18 AD patients. Only memory performance significantly …
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